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June 1, 2017

Fighting the CRISPR Lie

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Meet the new GM, same as the old GM.

 
 
Here’s the latest addition to the already substantial evidence of the danger and shoddiness of the CRISPR “gene editing” technique. In a medical research study the researchers wanted to find out how many mutations CRISPR really causes. Therefore they sequenced the entire genomes of the mice subjects instead of the usual procedure of sampling them according to a computer algorithm which predicts where mutations are likely to be. They found thousands of mutations not predicted by the algorithm.
 
The algorithm procedure is typical crackpot reductive science with little or no validity for the real world:
 

“These predictive algorithms seem to do a good job when CRISPR is performed in cells or tissues in a dish, but whole genome sequencing has not been employed to look for all off-target effects in living animals,” says co-author Alexander Bassuk, MD, PhD, professor of pediatrics at the University of Iowa….

“Researchers who aren’t using whole genome sequencing to find off-target effects may be missing potentially important mutations,” Dr. Tsang says. “Even a single nucleotide change can have a huge impact.”

 
We see how different the result is when the study focuses on something closer to reality, the whole genomes of test subjects.
 
 
Here’s the takeaways and talking points.
 
1. This is just the latest proof that gene editing causes an extreme number of mutations and therefore is unsafe.
 
The health dangers of the “new” GMOs are the same as for the old GMOs. Scrambled genomes, insertional and tissue culture mutations, and the effects of these: A gene producing too much or too little of a protein with toxic or other ill effects, producing the wrong protein with toxic effect, producing a misfolded protein with toxic effect (Mad Cow disease is caused by a misfolded protein), toxically excessive or foreign metabolites, gene or cell damage leading to cancer or any number of other severe and lethal diseases.
 
2. This is just the latest proof of how gene editing is highly imprecise.
 
Once again we see how any claim to precision will never be anything more than one of the standard lies of genetic engineering. And make no mistake – this is a willful, deliberate campaign of lying on the part of the scientific establishment, government regulators, and the mainstream media. We’re far past the point of it being possible to be honestly mistaken about any of this. Everyone knows “precision” was a lie from the beginning, so even those who willfully choose not to look at the specific evidence in the case of CRISPR still knows its alleged precision is being touted by the same old liars. We’re long past the point where it’s possible to have good faith trust in any corporation, or to advocate such trust. On the contrary, anyone from government or media who says or implies that we the people should trust any corporation is acting in the worst of bad faith.
 
3. In both these ways the “new” GMOs are nothing new. On the contrary they’re the same old GMOs. That’s why we should call them retread GMOs.
 
4. As in every other case, retread GM products like the Simplot potato and the botox apple are nothing but an inferior, more complex and expensive, less safe version of already existing non-GM varieties which are better, safer, and less expensive. Those are RNAi products; any future CRISPR products would be no different. We see how the retread GMOs, just like all previous GMOs, have no redeeming agronomic or social purpose. On the contrary their only purpose is corporate profit and control, and to feed the idiot fantasies of the scientism cult which worships inferior high-maintenance technology for its own sake. They believe because it’s absurd.
 
5. We must stress that there is nothing at all “unintended” about these effects. The effects of genetic engineering are grossly unpredictable, but this unpredictability is known and embraced ahead of time. “Unpredictable” has nothing conceptually in common with “unintended.” We can compare the typical operations of poison-based agriculture to spinning a roulette wheel where the various colors and numbers indicate various chaotic effects, many of them to be a surprise. Which number will come up is unpredictable, but one spins the wheel with full malice aforethought, full intent to trigger the chaos.
 
Genetic engineers and breeders involved in developing GM crops for commercial release have full knowledge of their inability to predict anything, therefore they intend chaotic results, just as they do with their broader mandate to drive climate change and pump as much synthetic poison into ecosystems as possible. The pro-GMO activists simply lie about all this when they make any claim to “precision” or predictability. No one who wanted stable, predictable results would still be working with genetic engineering. Where it comes to our food, agriculture, and environment, we’re not just spinning the roulette wheel. We’re playing Russian roulette, as Black Swan author Nassim Taleb put it.
 
Therefore I recommend to anyone interested in conceptual and terminological discipline that we discard the whole false notion of “unintended” effects of GMOs, pesticides, climate change, etc. This is factually wrong and morally far too lenient. Chaos is the predictable effect of genetic engineering, therefore the pro-GM activists intend chaos. That’s one of the purposes of this massive uncontrolled human feeding experiment, to log the unpredictable effects of the globally promiscuous deployment of GMOs in the environment and diet. They premeditate the chaos so they can hope someday to understand it, toward vastly further-reaching eugenic goals.
 
6. As a group the retread GMOs must be seen and publicly branded as nothing but a propaganda campaign trying to revamp the tattered image of GMOs, which are increasingly being seen in their true light as a shoddy, backward, regressive, reactionary technology dedicated to propping up the antiquated, proven failure of the paradigm of pesticide-based agriculture. Objectively, the retread campaign adds nothing new in any way at all.
 
The retreads also enable the legalistic and propaganda campaign of regulators like the USDA who want to abdicate all responsibility for GMO oversight. Lately I’ve been writing often about the need to relinquish all faith in government regulators and that this movement has the task of demolishing all public trust in regulatory agencies. Here’s yet more proof that the regulators are not on our side, serve no constructive purpose, and that we don’t need them: By the regulators’ own testimony they have no reason for being, since they themselves openly abdicate all responsibility for GM oversight.
 
 
 
Help propagate the abolitionist ideas.
 
 
 
 
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May 11, 2017

The “New” Old Monsanto, Attempting a Cult Revival

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For all its current power Monsanto has a bleak future. In a sector scrambling to consolidate because its real opportunities for the future are increasingly constrained, Monsanto is especially vulnerable. The company is dependent upon Roundup for about 70% of its revenues. Roundup accounts for half its sales, while GMOs dependent upon it make up much of the rest. That’s why Syngenta had little interest even in Monsanto’s GMO business. In 2015 the entire world learned for keeps what campaigners, Monsanto, and regulators have long known, that glyphosate causes cancer. With the WHO’s announcement the clock is now ticking, counting down the rest of glyphosate’s legal life. The people will now slowly but surely force the complete ban of glyphosate-based poisons. The bell is tolling for Roundup, Monsanto knows it, everyone knows it. They must find new products or die. They’re hyping everything in sight, from slapping new ad slogans on old, pointless, narrow-market products to touting the idea of RNA interference GMOs. But if these ever came to market they’d still be the same kind of shoddy insecticidal GMOs which in Bt form are already a failure with a gradually diminishing market.
 
The structural reason driving the current consolidation is that GMOs are a shoddy product and don’t have much of a market or a future in themselves. On the contrary, there’s a growing consensus inside and outside the sector, including on Wall Street, that the pesticides remain primary, with the GMOs being secondary to these and dependent upon them. Their fundamentals are bad. In other words the finance sector now agrees with what GMO critics have said from the start, that GMOs in the real world are nothing but pesticide plants, poison plants. Although Wall Street is poor at acknowledging its own pyramid schemes, it knows how to call them out in other sectors. GMOs are a scam.
 
By now all the GMO cartel has is the hype and hoaxes of the pro-GM activists and the corporate media. Monsanto in particular is desperate to tout its new GMO campaign, and with media fanfare is licensing two CRISPR “gene editing” processes. Monsanto’s Roundup business is seen as having a highly questionable future, and in all the merger talk the only thing which has really interested anyone is the company’s potential to develop GM traits other than those based on glyphosate. Here we see Monsanto desperate to reassure skeptical Bayer shareholders. Indeed, the hype over “new GMOs” may continue fooling the business world for awhile, but hype is all it is. As a practical way for the GMO project to get on track and start delivering on its promises, the retread GMOs are a vain ploy and a malign lie.
 
 
Here’s all anyone needs to know about CRISPR etc., the whole false notion of a retread “second generation” of GMOs based on “gene editing”, RNA interference, and similar tricks: These retreads are the same failed technology, the same failed GMOs, the same failed mode, the same failed agricultural paradigm based on poison, guaranteed to have the same result as all prior pesticides and GMOs. Pests will quickly overcome it, it will function only on the same ever-accelerating pesticide treadmill which already spins endlessly, it will poison people, animals, and the environment, and it will contaminate non-GM crops and wild plants. It’s not possible to be mistaken about any of this. Indeed, these are proven to be intentional primary effects of every technology deployed as part of poison-based agriculture. As its name says, this is the project of maximizing the production and use of poisons in order to maximize the poisoning of people and the Earth. All of this is being done for its own sake, as well as for the sake of profit and power. All of it is disguised with the lie that any of it has anything to do with producing food.
 
By now all we have are conscious, willful liars on the one hand, vast amounts of gratuitous, self-willed ignorance on the other, with a few scattered truth-tellers who recognize the clear facts.
 
The health dangers of the retread GMOs are the same as for the old GMOs. Scrambled genomes, insertional and tissue culture mutations, and the effects of these: A gene producing too much or too little of a protein with toxic or other ill effects, producing the wrong protein with toxic effect, producing a misfolded protein with toxic effect (Mad Cow disease is caused by a misfolded protein), toxically excessive or foreign metabolites, gene or cell damage leading to cancer or any number of other health destructions, “silencing” the genes of humans who come into contact (topical, inhaled, ingested) with the RNAi pesticide, and any number of other predictably unpredictable chaotic effects. The retread GMOs are the same as the old GMOs.
 
In the same way the health dangers are the same as for any other pesticide. The engineers and propagandists have no more idea how genotoxic, hormone disrupting, neurotoxic, organically toxic, and carcinogenic the RNAi pesticides will be than they originally had for the other classes of pesticides, all of which proved to be lethal to humans in all these ways. To put that another way, they know perfectly well that the RNAi pesticides will almost certainly have the same effects that all other pesticides have. The new pesticides are the same as the old pesticides, and will fail against pests and poison people in the same way the old ones always do.
 
It’s not possible to be mistaken about any of this. These are all known facts.
 
Of course the “new” retread GMOs are designed to aggravate the socioeconomic and political evils of corporate agriculture and commodity-based production the same way all previous GMOs were designed. Just like all prior GMOs, the goal of the retread GMOs is to starve the world in order to feed a handful of gluttons.
 
All the hype surrounding the new GMOs is based on the junk science of genetic determinism, same as for the old GMOs. In both cases the facts are:
 
1. On the most basic factual level, the engineers and their supporters have no idea what they’re doing. Jonathan Latham writes,
 

[The industry and media’s] exposition is belied by the evidence. If CRISPR were already precise, accurate and specific there would, for example, be no publications in prominent scientific journals titled “Improving CRISPR-Cas nuclease specificity using truncated guide RNAs“. And these would not begin by describing how ordinary CRISPR “can induce mutations at sites that differ by as many as five nucleotides from the intended target”, i.e. CRISPR may act at unknown sites in the genome where it is not wanted (Fu et al., 2014).

…[I]t is technically not possible to make a single (and only a single) genetic change to a genome using CRISPR and be sure one has done so (Fichtner et al., 2014). As Fichtner noted “in mammalian systems Cas9 causes a high degree of off-target effects”…There is, furthermore, no guarantee that more precise versions of CRISPR are even biologically possible. Technically therefore, precision is a myth: no form of genome editing can do what is currently being claimed.

 
2. In addition to their complete ignorance of ecology and agronomy, they know nothing about the science of genetics or biology. To believe in genetic determinism requires ignorance of even the most basic elements of the state of the science. Here’s Latham again.
 

[A] defined, discrete or simple pathway from gene to trait probably never exists. Most gene function is mediated murkily through highly complex biochemical and other networks that depend on many conditional factors, such as the presence of other genes and their variants, on the environment, on the age of the organism, on chance, and so forth. Geneticists and molecular biologists, however, since the time of Gregor Mendel, have striven to find or create artificial experimental systems in which environmental or any other sources of variation are minimised so as not to distract from the more “important” business of genetic discovery.

But by discarding organisms or traits that do not follow their expectations, geneticists and molecular biologists have built themselves a circular argument in favour of a naive deterministic account of gene function. Their paradigm habitually downplays the enormous complexities by which information passes (in both directions) between organisms and their genomes. It has created an immense and mostly unexamined bias in the default public understanding of genes and DNA.

 
Where this isn’t willful lying, it’s the common mode of being seduced by a crackpot version of “scientific method”. They reify these ivory tower experimental conditions of limited usefulness into the lie that these are real conditions which give real knowledge.
 
 
The primary lie making up the marketing campaign for the retread GMOs is that they’ve been made with extra-special “precision”. The propaganda theme that the retread GMOs have been engineered with precision is the exact same lie as the theme that the old GMOs were the result of precision engineering. In reality all genetic engineering is an extremely sloppy, wasteful, scattershot empirical process relying on brute force and massive reiteration to produce an adequate result once in awhile. Genetic engineering and its results is best represented by the proverbial stopped clock which is correct twice a day. So it’s been for all GMOs to date, and so it is for the “new” GMOs.
 
In itself, precision is only as intelligent or moronic as allowed by the extent of one’s knowledge. Latham gives a good analogy: “Suppose, as a non-Chinese speaker, I were to precisely remove from a Chinese text one character, one line, or one page. I would have one hundred percent precision, but zero control over the change in meaning. Precision, therefore, is only as useful as the understanding that underlies it.” In reality, even legitimate science knows little about the details of genomes and next to nothing about the chaotic genome effects of genetic engineering. When we add to this ignorance of the details and repercussions the engineers’ junk science of biological determinism and their complete ignorance of the state of genetic and biological science, we see how even if they did have a precision technique they’d still have absolutely no idea what they were doing. They’d be firing with good marksmanship into a soundless, pitch black void. But to say again, they have no precision technique either. They’re really hurling handfuls of gravel into that void.
 
The “precision” lie is a core article of the religious faith of scientism, going back centuries to the de jure Christian roots of the engineering ideology. Although engineers and scientists have never had such precision control of anything, they’ve always prayed to themselves and lied to the world that they did possess such precision knowledge and control. Here again, the hype about CRISPR is just the latest incarnation of the most hackneyed lies. Here too it’s not possible to be mistaken. Anyone familiar with the history of science and engineering, especially the history of pesticides and GMOs, knows the lie by heart.
 

Technologies based on the reductive, poisonist junk science like genetic engineering, artificial intelligence, synthetic “life”, robotics, nanotech, geoengineering and others share the fantasy of the engineer exercising total control through the precision use of control technologies and engineering techniques. Science has seldom been more than a servant of this cult religion of control. More often than not the process by which these technologies are developed has little to no “precision” involved, but is a very messy process based on profligate, wasteful deployment of brute force empiricism toward whatever approximate result is “close enough” in practice as long as it can be transformed through the fantasy into an idea of precision. In the same way, as a rule these technologies don’t work in the real world. The real world performance of GMOs ranges from temporarily adequate as long as supported by the most lavish, expensive panoply of inputs – bank credit, machinery, fertilizer, irrigation, pesticides – to a complete disaster from the start. Nowhere on Earth have GMOs ever consistently performed as well as the much healthier, much less expensive true crops. But as long as cheap oil, industrial inputs, and corporate welfare can provide enough brute force to keep GMOs in the field at all, this is enough for the scientism cultists and their fanboys to fetishize GMOs into a transcendent religious ideal.
 
When we consider the origin and circumstances of the STEM cadre this cultism isn’t surprising. STEM disciplines attract the most hierarchically-oriented, authoritarian, reductive, order-obsessed types who are also the most alienated from physical (ecological) reality and at the same time possessed of the most intense religiosity. In the modern era scientism and “Progress” have presented themselves as secular civil religions, but this pseudo-secularity is just a temporary variation on the Christian millennarian roots of technology worship and science ideology. For over 900 years inventors and practitioners of engineering and science explicitly saw themselves as imitating Adam in the Garden of Eden, creating in the image of the Creator, becoming co-Creators with God, and as preparing the human condition for the Second Coming. To this day these apocalyptic religious themes remain explicit and normative among aerospace and weapons engineers. It’s also standard rhetoric among AI cultists and “transhumanists”.
 
The explicit Christian rhetoric is also common among genetic engineers and GMO cultists, and the transcendent tone, evangelical attitude, and warnings/hopes of the imminent apocalypse are exactly the same. It’s the same millennarian Christian religiosity, even where temporarily submerged by civil religious ideology.
 
Given this extremist interior, the fact that the engineers usually must function as lower-level cogs in the corporate machine, obeying the dictates of executives and marketers, the whole endeavor just a subdivision of the much more comprehensive Mammon religion, must bother them. To give just one example, Lords of the Harvest describes the initial cultural conflict at Monsanto between the high-flown fantasies and pretensions of the genetic engineering division and the agrochemical division, which the genetic engineers at first disdained as a gang of backward luddites. It was only after the GE division put up a perfect record of failure over years of very expensive confusion that they finally lowered their sights and began working on poison plants. (They failed at this too; one day soon I’ll write a piece documenting Monsanto’s near-perfect record of failure and theft.)
 
When we put all this together, it’s no wonder the techno-cultists exalt the fantasy of precision and control and keep telling themselves and the world lies about it. And although they continue to tell these lies about the GMOs which have been deployed so far, at the same time they implicitly admit they were always lying about these when they hype the alleged “new” kinds of GMOs, even going so far as to deny these GMOs are GMOs, which also disparages the existing types. They’re trying first to convince themselves that this time the “precision” really is precise, the “control” real control. But it’s all nothing but a retread of the same old lies, same old failures, same old bottleneck.
 
Most profoundly, we see in these phenomena some of the sources of the indelible culture of the lie among technocrats and scientism cultists. Humanity should have demanded of the very first scientist, “What is Truth?” The idealization of some notion of Truth, which is touted as the ultimate justification of science, originated in Christian theology and to this day remains a religious justification. Scientific “Truth” is therefore Truth as revealed by religious transcendence. As the engineers and scientists constantly say, with their technology they seek to transcend reality – the environment, biology, mortality, the irrationality and emotionality of human beings, the physical Earth. Their will to truth means the will to another world, an otherworld, an afterworld. Their will to truth must go hand in hand with the cult of technology. This means their “Truth” has always been purely instrumental. So from both directions – Truth as a theological article, and Truth as whatever idea of control technology is able to effect, right down to boosting profit margins – the culture of the lie is inherent in the technological version of Truth. As with all fundamentalist cults, the scientism cult recognizes only its transcendent ideal and its day to day empirical work, but displays absolute faithlessness toward any and all day to day measures of fact or truth. As for science itself, for the STEM cult this is nothing but an appendage of instrumental engineering. At best it can sometimes serve as a methodological guide, but is most commonly a propaganda facade. Just as the pseudo-democratic, pseudo-political ideology which has supplanted classical liberalism is called “neoliberalism”, so bona fide science has become a fraudulent “neoscience” completely engulfed within the corporate science paradigm of today’s STEM establishment. Between this mercenary hijacking and the religious basis of science as such, there’s little left of the exalted, allegedly rationalistic Enlightenment mythology. It’s the practicing engineers and scientists themselves who present the most extreme manifestation of human irrationalism and human emotionalism, as well as malignity, faithlessness, and absolute practical nihilism. But in their minds they dwell in a cloud city presided over by their own god. They see their task as to wipe out the ecological reality of the real Earth and humanity and replace it with a technology-dominated co-Creation between themselves and this god. If humanity is to survive, we must put a stop to them.
 
Thus Monsanto’s media advertorials for its future CRISPR projects are more than just typical corporate media hype. Underlying this is the will of the cult to arise from the muck of the bogged-down GMO/pesticide project and transcend on the wings of the gloriously retreaded “new” version of the same old anti-scientific, failure-mongering notions. In the end the CRISPR hype is still just hype, still just the same old lies. But the goal is far more than just propping up the stock price. The goal is to reinvigorate the flagging religious crusade. In the end, since Monsanto has no practical basis for future profit and power, it hopes to harness the power of religion to keep itself on top.
 
 
 
Help propagate the necessary actions.
 
 
 
 

April 6, 2017

Retread GMOs

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The trendiest new lie about GMOs is the only thing new about them. This is the lie that there’s “new” kinds of what are really the same old GMOs.
 
Even the lie itself isn’t new. In form it simply repeats the hoary old debunked lie about the alleged “precision” of genetic engineering. The new version goes, “These new technologies really are precise, honest and for true this time!” These fake “new” versions of the same old extremely imprecise GMOs include CRISPR “gene editing” and similar “new breeding technologies”, RNA interference, gene drives, and synthetic biology. Sites like Independent Science News and SynBioWatch do excellent work describing in detail how these function and how scattershot and dangerous they are. As a group these need an appropriately informative and disparaging term like “retread GMOs.”
 
You don’t like GMOs? Look how they’re making GMOs even more radical, less precise, more chaotic, more potentially destructive. We already know there’s no overall precision and that genetic engineers have no idea what they’re doing. Therefore every time you hear anyone from the system say they’re becoming more “precise” you know this is nothing but a measure of their deepening delusion, and of their constant will to force their kind of manipulation and control over all of humanity and nature.
 
In general “experts” never sustain competence because their egomania and congenital drive toward ever greater manipulation and the idea of control always trump any desire they may have for true understanding and competence.
 
Thus, even if on rare occasions knowledge and practice actually were to stabilize, and the experts of the moment really did understand what they were doing, they could never remain stable at this position. They quickly would drive the situation into chaotic territory, and therefore they quickly would revert to incomprehension and incompetence. The more extremely high-energy and high-maintenance technology and its support structures become, the more wasteful and destructive the results of this incompetence become. The only thing reliably constructed is the further concentration of wealth and power, for as long as the corporate technocratic system exists, until its incompetence, wastefulness, and destructiveness become so extreme that the system consumes and destroys itself. Therefore a core task of the abolition movement is to conserve itself through this period of technocracy’s self-destruction.
 
If the Peter Principle is a law of system hierarchies (and goes some way toward describing the self-wastefulness and self-destructiveness), we can adduce a companion principle which applies to every type of technical expert: Their inertia always is strongly toward the zone of incomprehension and incompetence. Experts are not conservatives and never seek to conserve understanding and competence. They’re always nihilistic radicals, bomb-throwers. A core task of the abolition movement is to conserve real knowledge, real science, real competence, and abolish the fake versions along with the nihilism that drives them.
 
With the retread GMOs the engineers simply are retreading their previous paths of imprecision, incomprehension, willfully driven chaos, willfully driven waste and destruction. As with previous GMOs, they have no idea of the complexity of the effects of their “new” techniques. Even where the technical procedure seems superficially more “precise”, its chaotic effects are every bit as unpredictable as the most blunderbussing gene gun. Even the most precise cut can have extreme chaotic effects. Meanwhile, faster “sequencing” capabilities give engineers only the same small, uncontexted fragment of information they had before. It merely speeds up ignorance and enhances the arrogance of stupidity which is the defining trait of technocrats.
 
Genetic engineering aspires to bring all of life under technological control and eugenic manipulation. The escalated use of computerized mechanization to perform the engineering is designed to escalate this program of control and manipulation by further removing the concept of life from the realm of ecology and into the realm of software and data manipulation. This is the better to deny evolution and disparage ecology, and bring real life under the conceptual, and eventually the actual physical control of eugenic technology and legalistic computer and intellectual property fictions. This is another manifestation of Monsanto’s original plan to become the “Microsoft of agriculture”, with its transgenic traits serving as the hegemonic “software” controlling all the stupid “hardware” of agriculture and food. The ultimate goal of course is to attain this reified control over all of physical reality.
 
This notion of attaining physical dominion and control via computer data and its synthesized physical extension, including fantasies about artificial intelligence, is a typical fiction of the Mammon and scientism religions. Bits of code are just another fictive number, and all cults stemming from them are just another branch of numerology.
 
Mammon usually is conceived as greed or, more precisely, the belief that money is real, and the religious worship of this reified money. But this can be boiled down further to the belief that fictive numbers are real, and the worship of these numbers. Love of money is just the most common and visible form of this cult worship. But this kind of worship also is the core of the scientism/technocracy religion.
 
If science is the branch of philosophy that focuses on developing methods to produce precise numbers as a conception and reflection of the qualitative diversity of reality, then scientism is the religious cult which then is built by the practitioners of science and their followers. They reify these numbers, convince themselves the numbers in themselves are “real” rather than a philosophical abstraction, and turn reality completely upside down by convincing themselves that this superficial abstraction of reality is actually the true reality, and actual reality just the abstraction. (Thus they recapitulate the program of the British and German solipsistic philosophers.) They come to worship these numbers. And since they can manipulate the numbers at will, it follows that actual physical reality, to them a mere abstraction, also is infinitely manipulable at their command. In this way they use the religious vehicle of numerology to transform themselves, in their own minds, into gods. This sums up their religious belief system.
 
Their preferred propaganda term “new breeding technologies” (NBT) is a window into their mindset. They claim we need new techniques since sexuality within the framework of evolution is, according to technocracy, insufficient. This begs the question, “insufficient for what?” Self-evidently evolution is sufficient for the entire reality of humanity and the Earth. It could be insufficient only from the perspective of a radically anti-human, anti-ecological, anti-evolution agenda. This is indeed the totalitarian agenda of technocracy.
 
 
From there it’s easy to see how the worshipers of pseudo-scientific numbers join hands with the worshipers of monetary numbers, and how easily these fraternal sects always have worked together. They’re two shades of the same color. Because they share the goal of using their numbers to attain control of humanity and the Earth, they’ve always easily formed a strategic and tactical alliance for their political, economic, and ecological assaults.
 
 
It’s self-evident that such a monstrous campaign of religious fanaticism cannot be “regulated”. To use the terminology of the system regulation paradigm, it can’t be “managed”, can’t be “risk-assessed”, humanity cannot set “tolerances” for it. The fact is humanity and the Earth cannot co-exist with corporate scientism. We must abolish it, its mindset, its crimes. Therefore we need to propagate the abolition idea and build the abolition movement.
 
Unfortunately there’s another standard retread going on, and that’s the retread among critics of GMOs and poisonism who seem unable to liberate themselves from the “regulation” paradigm. Indeed, this paradigm is itself part of technocracy, and the unreconstructed pro-regulation types reveal themselves to be waging a campaign of reformism within the framework of corporate technocracy, including the framework of considering corporate dominion and genetic engineering to be normative. Indeed, by their own testimony many of these persons are pro-GMO. Often they openly admit their support for laboratory testing of GMOs and for fraudulent medical applications of genetic engineering. They oppose only specially selected agricultural applications, evidently on an arbitrary basis.
 
But this basis cannot provide the necessary philosophical and spiritual foundation of humanity’s great resistance and liberation movement. Worse, it seeks to keep all thought and action imprisoned within the framework of “co-existence” with poisonism within the technocratic framework. But co-existence is impossible, and propaganda for it is evil.
 
It often is worthwhile to condemn the system’s refusal to perform real safety tests, refusal to undertake real regulation, refusal to properly label GMOs, refusal to enforce existing laws which require banning cancer agents, and its general refusal to act according to the principles of need, alternatives, and precaution, when this criticism is undertaken within the context of an explicit abolitionist framework. (Most pertinently, these derelictions comprise strict proof that the system knows or believes pesticides and GMOs to be extremely harmful to human and environmental health. Therefore its motive in forcing them upon humanity and the Earth must be malignant.) But to cite these for their own sake automatically presumes the impossible and pernicious co-existence framework. And of course to still advocate, as one’s actual program, things like labeling, “better testing”, and the precautionary principle, all those ships that sailed so long ago, is by now nothing but reactionary.
 
Therefore the point no longer is to say “we need better EPA regulation of pesticides”, or “CRISPR needs to be regulated as other GMOs” (the same people who say this also acknowledge that regulation of regular GMOs was never adequate), but rather:
 
We know that all pesticides are cancerous, don’t work anyway, and never can be “regulated”. Therefore we must abolish them completely.
 
We know that all genetic engineering is extremely imprecise and chaotic, highly dangerous, has never worked for its avowed purposes, and has no constructive purpose. Therefore we must abolish it completely.
 
 
 
 
 
Help propagate the new and necessary ideas.
 
 
 

April 27, 2016

The Whole False Notion: “Precision”, Genetic Engineering, and GMOs

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Here’s all anyone needs to know about CRISPR etc., the whole false notion of a “second generation” of GMOs based on “gene editing”, RNA interference, and similar tricks: These are the same failed technology, the same failed GMOs, the same failed mode, the same failed agricultural paradigm based on poison, guaranteed to have the same result as all prior pesticides and GMOs. Pests will quickly overcome it, it will function only on the same ever-accelerating pesticide treadmill which already spins endlessly, it will poison people, animals, and the environment, and it will contaminate non-GM crops and wild plants. It’s not possible to be mistaken about any of this. Indeed, these are proven to be intentional primary effects of every technology deployed as part of poison-based agriculture. As its name says, this is the project of maximizing the production and use of poisons in order to maximize the poisoning of people and the Earth. All of this is being done for its own sake, as well as for the sake of profit and power. All of it is disguised with the lie that any of it has anything to do with producing food.
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By now all we have are conscious, willful liars on the one hand, vast amounts of gratuitous, self-willed ignorance on the other, with a few scattered truth-tellers who recognize the clear facts.
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The health dangers of the “new” GMOs are the same as for the old GMOs. Scrambled genomes, insertional and tissue culture mutations, and the effects of these: A gene producing too much or too little of a protein with toxic or other ill effects, producing the wrong protein with toxic effect, producing a misfolded protein with toxic effect (Mad Cow disease is caused by a misfolded protein), toxically excessive or foreign metabolites, gene or cell damage leading to cancer or any number of other health destructions, “silencing” the genes of humans who come into contact (topical, inhaled, ingested) with the RNAi pesticide, and any number of other predictably unpredictable chaotic effects. The new GMOs are the same as the old GMOs.
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In the same way the health dangers are the same as for any other pesticide. The engineers and propagandists have no more idea how genotoxic, hormone disrupting, neurotoxic, organically toxic, and carcinogenic the RNAi pesticides will be than they originally had for the other classes of pesticides, all of which proved to be lethal to humans in all these ways. To put that another way, they know perfectly well that the RNAi pesticides will almost certainly have the same effects that all other pesticides have. The new pesticides are the same as the old pesticides, and will fail against pests and poison people in the same way the old ones always do.
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It’s not possible to be mistaken about any of this. These are all known facts.
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Of course the “new” GMOs are designed to aggravate the socioeconomic and political evils of corporate agriculture and commodity-based production the same way all previous GMOs were designed. Just like all prior GMOs, the goal of the new GMOs is to starve the world in order to feed a handful of gluttons.
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All the hype surrounding the new GMOs is based on the junk science of genetic determinism, same as for the old GMOs. In both cases the facts are:
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1. On the most basic factual level, the engineers and their supporters know vastly less than they claim to know. Jonathan Latham writes,
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[The industry and media’s] exposition is belied by the evidence. If CRISPR were already precise, accurate and specific there would, for example, be no publications in prominent scientific journals titled “Improving CRISPR-Cas nuclease specificity using truncated guide RNAs“. And these would not begin by describing how ordinary CRISPR “can induce mutations at sites that differ by as many as five nucleotides from the intended target”, i.e. CRISPR may act at unknown sites in the genome where it is not wanted (Fu et al., 2014).

Thus CRISPR itself will need tweaking before it can be useful for safe commercial products, and that is the first error of the tweaking argument. So far, it is technically not possible to make a single (and only a single) genetic change to a genome using CRISPR and be sure one has done so (Fichtner et al., 2014). As Fichtner noted “in mammalian systems Cas9 causes a high degree of off-target effects”. And at least until modified versions come into use, this will limit the safety, and hopefully limit the application, of CRISPR and related biotechnologies. There is, furthermore, no guarantee that more precise versions of CRISPR are even biologically possible. Technically therefore, precision is a myth: no form of genome editing can do what is currently being claimed.

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2. They know nothing about the science of genetics or biology. (Not to mention ecology and agronomy.) To believe in genetic determinism requires ignorance of even the most basic elements of the state of the science. Here’s Latham again.
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[A] defined, discrete or simple pathway from gene to trait probably never exists. Most gene function is mediated murkily through highly complex biochemical and other networks that depend on many conditional factors, such as the presence of other genes and their variants, on the environment, on the age of the organism, on chance, and so forth. Geneticists and molecular biologists, however, since the time of Gregor Mendel, have striven to find or create artificial experimental systems in which environmental or any other sources of variation are minimised so as not to distract from the more “important” business of genetic discovery.

But by discarding organisms or traits that do not follow their expectations, geneticists and molecular biologists have built themselves a circular argument in favour of a naive deterministic account of gene function. Their paradigm habitually downplays the enormous complexities by which information passes (in both directions) between organisms and their genomes. It has created an immense and mostly unexamined bias in the default public understanding of genes and DNA.

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Where this isn’t willful lying, it’s the common mode of being seduced by a crackpot version of “scientific method”. They reify these ivory tower experimental conditions of limited usefulness into real conditions which give real knowledge.
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The primary lie making up the marketing campaign for the “new” GMOs is that they’ve been made with extra-special “precision”. The propaganda theme that the new GMOs have been engineered with precision is the exact same lie as the theme that the old GMOs were the result of precision engineering. In reality all genetic engineering is an extremely sloppy, wasteful, scattershot empirical process relying on brute force and massive reiteration to produce an adequate result once in awhile. Genetic engineering and its results is best represented by the proverbial stopped clock which is correct twice a day. So it’s been for all GMOs to date, and so it is for the “new” GMOs.
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In itself, precision is only as intelligent or moronic as allowed by the extent of one’s knowledge. Latham gives a good analogy: “Suppose, as a non-Chinese speaker, I were to precisely remove from a Chinese text one character, one line, or one page. I would have one hundred percent precision, but zero control over the change in meaning. Precision, therefore, is only as useful as the understanding that underlies it.” In reality, even legitimate science knows little about the details of genomes and next to nothing about the chaotic genome effects of genetic engineering. When we add to this ignorance of the details and repercussions the engineers’ junk science of biological determinism and their complete ignorance of the state of genetic and biological science, we see how even if they did have a precision technique they’d still have absolutely no idea what they were doing. They’d be firing with good marksmanship into a soundless, pitch black void. But to say again, they have no precision technique either. They’re really hurling handfuls of gravel into that void.
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The “precision” lie is a core article of the religious faith of scientism, going back centuries to the de jure Christian roots of the engineering ideology. Although engineers and scientists have never had such precision control of anything, they’ve always prayed to themselves and lied to the world that they did possess such precision knowledge and control. Here again, the hype about CRISPR is just the latest incarnation of the most hackneyed lies. Here too it’s not possible to be mistaken. Anyone familiar with the history of science and engineering, especially the history of pesticides and GMOs, knows the lie by heart.
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Technologies based on the reductive, poisonist junk science like genetic engineering, artificial intelligence, synthetic “life”, robotics, nanotech, geoengineering and others share the fantasy of the engineer exercising total control through the precision use of control technologies and engineering techniques. Science has seldom been more than a servant of this cult religion of control. More often than not the process by which these technologies are developed has little to no “precision” involved, but is a very messy process based on profligate, wasteful deployment of brute force empiricism toward whatever approximate result is “close enough” in practice as long as it can be transformed through the fantasy into an idea of precision. In the same way, as a rule these technologies don’t work in the real world. The real world performance of GMOs ranges from temporarily adequate as long as supported by the most lavish, expensive panoply of inputs – bank credit, machinery, fertilizer, irrigation, pesticides – to a complete disaster from the start. Nowhere on Earth have GMOs ever consistently performed as well as the much healthier, much less expensive true crops. But as long as cheap oil, industrial inputs, and corporate welfare can provide enough brute force to keep GMOs in the field at all, this is enough for the scientism cultists and their fanboys to fetishize GMOs into a transcendent religious ideal.
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When we consider the origin and circumstances of the STEM cadre this cultism isn’t surprising. STEM disciplines attract the most hierarchically-oriented, authoritarian, reductive, order-obsessed types who are also the most alienated from physical (ecological) reality and at the same time possessed of the most intense religiosity. In the modern era scientism and “Progress” have presented themselves as secular civil religions, but this pseudo-secularity is just a temporary variation on the Christian millennarian roots of technology worship and science ideology. For over 900 years inventors and practitioners of engineering and science explicitly saw themselves as imitating Adam in the Garden of Eden, creating in the image of the Creator, becoming co-Creators with God, and as preparing the human condition for the Second Coming. To this day these apocalyptic religious themes remain explicit and normative among aerospace and weapons engineers. It’s also standard rhetoric among AI cultists and “transhumanists”.
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The explicit Christian rhetoric is also common among genetic engineers and GMO cultists, and the transcendent tone, evangelical attitude, and warnings/hopes of the imminent apocalypse are exactly the same. It’s the same millennarian Christian religiosity, even where temporarily submerged by civil religious ideology.
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Given this extremist interior, the fact that the engineers usually must function as lower-level cogs in the corporate machine, obeying the dictates of executives and marketers, the whole endeavor just a subdivision of the much more comprehensive Mammon religion, must bother them. To give just one example, Lords of the Harvest describes the initial cultural conflict at Monsanto between the high-flown fantasies and pretensions of the genetic engineering division and the agrochemical division, which the genetic engineers at first disdained as a gang of backward luddites. It was only after the GE division put up a perfect record of failure over years of very expensive confusion that they finally lowered their sights and began working on poison plants. (They failed at this too; one day soon I’ll write a piece documenting Monsanto’s near-perfect record of failure and theft.)
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When we put all this together, it’s no wonder the techno-cultists exalt the fantasy of precision and control and keep telling themselves and the world lies about it. And although they continue to tell these lies about the GMOs which have been deployed so far, at the same time they implicitly admit they were always lying about these when they hype the alleged “new” kinds of GMOs, even going so far as to deny these GMOs are GMOs, which also disparages the existing types. They’re trying first to convince themselves that this time the “precision” really is precise, the “control” real control.
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Most profoundly, we see in these phenomena some of the sources of the indelible culture of the lie among technocrats and scientism cultists. Humanity should have demanded of the very first scientist, “What is Truth?” The idealization of some notion of Truth, which is touted as the ultimate justification of science, originated in Christian theology and to this day remains a religious justification. Scientific “Truth” is therefore Truth as revealed by religious transcendence. As the engineers and scientists constantly say, with their technology they seek to transcend reality – the environment, biology, mortality, the irrationality and emotionality of human beings, the physical Earth. Their will to truth means the will to another world, an otherworld, an afterworld. Their will to truth must go hand in hand with the cult of technology. This means their “Truth” has always been purely instrumental. So from both directions – Truth as a theological article, and Truth as whatever idea of control technology is able to effect, right down to boosting profit margins – the culture of the lie is inherent in the technological version of Truth. As with all fundamentalist cults, the scientism cult recognizes only its transcendent ideal and its day to day empirical work, but displays absolute faithlessness toward any and all day to day measures of fact or truth. As for science itself, for the STEM cult this is nothing but an appendage of instrumental engineering. At best it can sometimes serve as a methodological guide, but is most commonly a propaganda facade. Just as the pseudo-democratic, pseudo-political ideology which has supplanted classical liberalism is called “neoliberalism”, so bona fide science has become a fraudulent “neoscience” completely engulfed within the corporate science paradigm of today’s STEM establishment. Between this mercenary hijacking and the religious basis of science as such, there’s little left of the exalted, alleged rationalistic Enlightenment mythology. It’s the practicing engineers and scientists themselves who present the most extreme manifestation of human irrationalism and human emotionalism, as well as malignity, faithlessness, and absolute practical nihilism. But in their minds they dwell in a cloud city presided over by their own god. They see their task as to wipe out the ecological reality of the real Earth and humanity and replace it with a technology-dominated co-Creation between themselves and this god. If humanity is to survive, we must put a stop to them.
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